Analysis of indicators of caries of permanent teeth in children according to the endemic features of the Poltava region, Ukraine.

OBJECTIVE: Aim: This research is focused at analyzing the indicators and substantiating the peculiarities of caries prevention in permanent teeth in schoolchildren of Poltava region, taking into account the endemic features of the Poltava region. PATIENTS AND METHODS: Materials and Methods: A comparative study was conducted among 608 pupils of secondary schools in Kremenchuk, who consumed drinking water with fluoride concentrations in the lower limits of the norm, and 1214 pupils of secondary schools in Poltava, who consumed drinking water with fluoride concentrations in the optimal upper limits of the norm. RESULTS: Results: The rates of caries in permanent teeth in children living in a region with fluoride concentrations in drinking water in the optimal-upper normal range are several times lower than in children of the same age living in a region with fluoride concentrations in drinking water in the lower normal range, and a significant increase in the prevalence and intensity of caries is observed from 7 to 9 to 12 years of age, as teeth after eruption are most vulnerable to caries. In a region where the fluoride concentration in drinking water is in the optimal-upper range of the norm, children with early forms of fluorosis have the lowest prevalence and intensity of caries. CONCLUSION: Conclusions: Endemic features of the region directly affect the prevalence and intensity of the caries process. In regions with a fluoride concentration in drinking water within the optimal upper limits of the norm, prevention of caries in permanent teeth in children should be carried out taking into account the presence of fluorosis.

NEUTROPHIL ACTIVITIES IN ADOLESCENTS WITH TYPE I DIABETES MELLITUS DEPENDING ON PERIODONTAL STATE.

OBJECTIVE: The aim: To estimate the neutrophil activities in adolescents with type 1 diabetes mellitus (T1DM) depending on periodontal state. PATIENTS AND METHODS: Materials and methods: A total of 93 individuals aged 12-16 years, including 62 T1DM patients and 31 healthy (H) controls, were included. Both groups were categorized into subgroups depending on their periodontal state. Phagocytic activity of neutrophils (PAN) the index of neutrophil activation (INA), and the percent of formazan-active neutrophils were evaluated using the spontaneous and the induced nitroblue tetrazolium (sNBT and iNBT) tests into oral rinses. RESULTS: Results: PAN was significantly higher in the healthy (H) controls with gingivitis compared with the individuals with gingival health (p < 0.0001). This parameter decreased significantly in the T1DM subjects, especially with periodontitis, compared with the H controls (p < 0.0001). The percent of formazan-active neutrophils and INA in the sNBT test increased in the T1DM patients with gingival health and continued to raise as periodontal state of adolescents with T1DM worsened (p<0.0001). The parameters of the iNBT test in the T1DM adolescents decreased with the periodontal disease development (p < 0.0001) that may demonstrate that superoxide production exhausts in diabetes, especially associated with periodontal disease. CONCLUSION: Conclusions: The sNBT test in studied adolescents showed that both periodontal disease and T1DM increase the rate of activated neutrophils (p<0,05).

STUDYING THE RISK FACTORS OF CARIES IN THE FIRST PERMANENT MOLARS IN CHILDREN DEPENDING ON THEIR ODONTOGLIFICS.

OBJECTIVE: The aim: To study the prevalence of odontoglyphic variants of the first permanent molars of the lower jaw in children 6-7 years old, as well as the frequency of caries lesions in molars with the most common types of patterns on their chewing surface. PATIENTS AND METHODS: Materials and methods: We studied 1092 mandibular molars in 564 children without background pathology at the age of 6-7 years. The dynamics of the occurrence of fissure caries was studied in 347 first permanent molars of the lower jaw for 2 years and 246 molars in 155 children from among those observed during 3 years of the study. RESULTS: Results: In the children examined by us, the most common types of the chewing surface of the first permanent molars of the lower jaw were Y5- and + 5 patterns. We did not find a difference in the frequency of occurrence of these types in the surveyed girls and boys (p > 0.05). Our study showed that most often the first permanent molars of the lower jaw were affected by caries in the first 2 years of follow-up. The incidence of affection of the lower molars, which had a more complex structure of the occlusal surface (type Y5 and +5), was significantly higher than that of molars with the type of chewing surface +4. CONCLUSION: Conclusions: It has been established that in children 6-7 years old, the first permanent molars of the lower jaw have a more complex structure of the chewing surface, and the intensity of their caries damage is maximally high in the first two years after eruption and require active additional preventive measures in the early terms after their eruption.